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Aphidicolin is a diterpene fungal metabolite that blocks the cell cycle at early S-phase. In addition, Aphidicolin is a tetracyclic diterpene antibiotic with antiviral and antimitotic properties. Aphidicolin is a specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses of animal origin. Aphidicolin is useful for cell synchronization. Aphidicolin prolongs the half life of DNA methyltransferase. Aphidicolin acts synergistically with vincristine and doxorubicin. Aphidicolin is also known as APC, ICI 69653, ICI-69653, ICI69653, and (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[4-(1H-Pyrazol-1-yl)phenyl]acrylic acid, 500 mg | sc-310705 | 500 mg | $146.00 | |||
3-[4-(1H-Pyrazol-1-yl)phenyl]acrylic acid, 1 g | sc-310705A | 1 g | $203.00 |