Molecular structure of 3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester, CAS Number: 81069-02-5
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester (CAS 81069-02-5)
Alternate Names:
3,3′-Dithiobis(sulphosuccinimidyl propionate); DTSSP
Application:
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester is a water soluble and cleavable amine-reactive crosslinker
CAS Number:
81069-02-5
Purity:
≥94%
Molecular Weight:
564.54
Molecular Formula:
C14H16N2O14S4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester is a cross-linking reagent used extensively in biochemical and molecular biology research. This compound is particularly noted for its ability to form stable links between two sulfhydryl groups, often found in proteins or peptides. The sulfosuccinimidyl groups within the chemical structure of 3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester react with primary amines at physiological pH, allowing for the conjugation of molecules in a specific and controlled manner. This specificity makes it an invaluable tool for studying protein-protein interactions, enzyme-substrate relationships, and the structural and functional aspects of protein complexes.
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester (CAS 81069-02-5) References
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- N-hydroxysulfosuccinimide active esters: bis(N-hydroxysulfosuccinimide) esters of two dicarboxylic acids are hydrophilic, membrane-impermeant, protein cross-linkers. | Staros, JV. 1982. Biochemistry. 21: 3950-5. PMID: 7126526
- Tektins are heterodimeric polymers in flagellar microtubules with axial periodicities matching the tubulin lattice. | Pirner, MA. and Linck, RW. 1994. J Biol Chem. 269: 31800-6. PMID: 7527396
- Development of porous defects in plasma membranes of adenosine triphosphate-depleted Madin-Darby canine kidney cells and its inhibition by glycine. | Dong, Z., et al. 1998. Lab Invest. 78: 657-68. PMID: 9645756
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester, 100 mg | sc-206694 | 100 mg | $296.00 |