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3,3prime-Dipropylthiadicarbocyanine iodide is used for transmembrane potential measurements. This cationic dye accumulates on hyperpolarized membranes and is translocated into the lipid bilayer. It can be utilized in fluorescence microscopy to visualize changes in membrane potential of cells. It is often used to monitor the activity of ion channels, assess cell viability, or study membrane dynamics. 3,3prime-Dipropylthiadicarbocyanine iodide increases intracellular sodium levels, and decreases intracellular potassium levels in Ehrlich ascites tumor cells, as well as increases potassium membrane permeability in Ehrlich ascites tumor cells in the presence of the Na+/K+-ATPase inhibitor ouabain. It also reduces cellular ATP levels in the absence of glucose and induces acid production and inhibits oxygen consumption in the presence of glucose in Ehrlich ascites tumor cells.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,3′-Dipropylthiadicarbocyanine iodide, 100 mg | sc-209690 | 100 mg | $274.00 |