Date published: 2025-10-19

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3,3′-Dipropylthiacarbocyanine iodide (CAS 53336-12-2)

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Alternate Names:
DiSC3(3))
Application:
3,3′-Dipropylthiacarbocyanine iodide is used to monitor changes in the cellular and mitochondrial membrane potential.
CAS Number:
53336-12-2
Molecular Weight:
520.49
Molecular Formula:
C23H25IN2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,3′-Dipropylthiacarbocyanine iodide is used to monitor changes in the cellular and mitochondrial membrane potential. It is a fluorescent dye used as an optical probe of membrane potential. Depolarization of the plasma membrane potential is due to an increase in the fluorescence intensity of the dye.


3,3′-Dipropylthiacarbocyanine iodide (CAS 53336-12-2) References

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  2. Antifungal effect and mode of action of glochidioboside against Candida albicans membranes.  |  Lee, H., et al. 2014. Biochem Biophys Res Commun. 444: 30-5. PMID: 24434147
  3. Fungicidal effect of isoquercitrin via inducing membrane disturbance.  |  Yun, J., et al. 2015. Biochim Biophys Acta. 1848: 695-701. PMID: 25445674
  4. Detection of inhibitors of Candida albicans Cdr transporters using a diS-C3(3) fluorescence.  |  Szczepaniak, J., et al. 2015. Front Microbiol. 6: 176. PMID: 25806026
  5. A novel antimicrobial peptide, scolopendin, from Scolopendra subspinipes mutilans and its microbicidal mechanism.  |  Lee, W., et al. 2015. Biochimie. 118: 176-84. PMID: 26342880
  6. Antibacterial Mechanism of (-)-Nortrachelogenin in Escherichia coli O157.  |  Lee, H., et al. 2016. Curr Microbiol. 72: 48-54. PMID: 26420306
  7. (-)-Nortrachelogenin from Partrinia scabiosaefolia elicits an apoptotic response in Candida albicans.  |  Lee, H., et al. 2016. FEMS Yeast Res. 16: PMID: 26880798
  8. Kinetic Measurements of Di- and Tripeptide and Peptidomimetic Drug Transport in Different Kidney Regions Using the Fluorescent Membrane Potential-Sensitive Dye, DiS-C3-(3).  |  Alghamdi, OA., et al. 2017. J Membr Biol. 250: 641-649. PMID: 28988287
  9. Apigenin induces cell shrinkage in Candida albicans by membrane perturbation.  |  Lee, H., et al. 2018. FEMS Yeast Res. 18: PMID: 29346565
  10. Three fluorescent probes for the flow-cytometric assessment of membrane potential in Saccharomyces cerevisiae.  |  Denksteinová, B., et al. 1996. Folia Microbiol (Praha). 41: 237-42. PMID: 9449773

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,3′-Dipropylthiacarbocyanine iodide, 250 mg

sc-209689
250 mg
$102.00