Molecular structure of 3,3′-Diiodo-L-thyronine, CAS Number: 4604-41-5
3,3′-Diiodo-L-thyronine (CAS 4604-41-5)
See product citations (2)
Alternate Names:
T2
Application:
3,3′-Diiodo-L-thyronine is a partially deiodized thyroxine derivative
CAS Number:
4604-41-5
Purity:
98%
Molecular Weight:
525.08
Molecular Formula:
C15H13I2NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3,3′-Diiodo-L-thyronine is a thyroid hormone that specifically binds to the DNA response element situated in the promoter region of its target genes. 3,3′-Diiodo-L-thyronine additionally exhibits the ability to impede the production of hydrochloric acid. The presence of 3,3′-Diiodo-L-thyronine can be detected in serum as early as 3 hours post-ingestion, and its quantification can be achieved using high-performance liquid chromatography with electrochemical detection. It is important to consider the occurrence of the matrix effect, wherein different analytical methods can impact the analysis of samples, requiring careful interpretation of results.
3,3′-Diiodo-L-thyronine (CAS 4604-41-5) References
- Mechanism of molecular recognition. Structural aspects of 3,3'-diiodo-L-thyronine binding to human serum transthyretin. | Wojtczak, A., et al. 1992. J Biol Chem. 267: 353-7. PMID: 1730601
- Binding characteristics of a major thyroid hormone metabolite, 3,3',5'-triiodo-L-thyronine, to bovine serum albumin as measured by fluorescence. | Okabe, N., et al. 1989. Biochim Biophys Acta. 990: 303-5. PMID: 2923909
- Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. | Lanni, A., et al. 1994. Mol Cell Endocrinol. 99: 89-94. PMID: 8187965
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DIO2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,3′-Diiodo-L-thyronine, 1 mg | sc-206692 | 1 mg | $207.00 |