3,3′-Dihexyloxacarbocyanine Iodide is a cationic, voltage-sensitive, cell-permeable, lipophilic, green fluorescent, carbocyanine dye which is utilized as a membrane potential probe. At a low concentration, the dye will selectively stain the mitochondria of live cells. At high concentrations the dye will stain the endoplasmic reticulum and other internal membranes. 3,3′-Dihexyloxacarbocyanine Iodide is a photosensitizer that photodamages microtubules. It is also utilized as an electron transport inhibitor and may be used as a probe to study multi-drug-resistant cells.
1. Lee, C., et al. 1995. Cancer Res. 55: 2063-2069. PMID: 7743503 2. Rottenberg, H., et al. 1997. Biochem. Biophys. Res. Commun. 240: 68-74. PMID: 9367884 3. Sabnis, R.W., et al. 1997. Biotech. Histochem. 72: 253-258. PMID: 9408585
Soluble in ethanol, water (partly miscible), methanol, and DMSO.
Store at 4° C
219-221° C (lit.)
λex 485 nm, λem 501 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Great for Membrane staining in mouseWorked! 1:200 for WB on NIH/3T3 with 30min incubation. Used direct conjugate sc-324-AC
Date published: 2018-09-19
Rated 5 out of
Various publications cite the use of 3Various publications cite the use of 3,3 -Dihexyloxacarbocyanine Iodide, a cationic, voltage-sensitive, cell-permeable, lipophilic, green fluorescent, carbocyanine dye, as a membrane potential probe. At a low concentration, the dye will selectively stain the mitochondria of live cells. At high concentrations the dye will stain the endoplasmic reticulum and other internal membranes. -SCBT Publication Review
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