3,3prime-Dihexyloxacarbocyanine Iodide CAS: 53213-82-4
MF: C29H37IN2O2
MW: 572.52
A membrane potential green fluorescent probe.

3,3′-Dihexyloxacarbocyanine Iodide (CAS 53213-82-4)

3,3′-Dihexyloxacarbocyanine Iodide | CAS 53213-82-4 is rated 5.0 out of 5 by 2.
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Synonym: DiOC6(3)
Application: A membrane potential green fluorescent probe
CAS Number: 53213-82-4
Purity: ≥95%
Molecular Weight: 572.52
Molecular Formula: C29H37IN2O2
* Refer to Certificate of Analysis for lot specific data (including water content).
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3,3′-Dihexyloxacarbocyanine Iodide is a cationic, voltage-sensitive, cell-permeable, lipophilic, green fluorescent, carbocyanine dye which is utilized as a membrane potential probe. At a low concentration, the dye will selectively stain the mitochondria of live cells. At high concentrations the dye will stain the endoplasmic reticulum and other internal membranes. 3,3′-Dihexyloxacarbocyanine Iodide is a photosensitizer that photodamages microtubules. It is also utilized as an electron transport inhibitor and may be used as a probe to study multi-drug-resistant cells.


References

1. Lee, C., et al. 1995. Cancer Res. 55: 2063-2069. PMID: 7743503
2. Rottenberg, H., et al. 1997. Biochem. Biophys. Res. Commun. 240: 68-74. PMID: 9367884
3. Sabnis, R.W., et al. 1997. Biotech. Histochem. 72: 253-258. PMID: 9408585

Physical State :
Solid
Solubility :
Soluble in ethanol, water (partly miscible), methanol, and DMSO.
Storage :
Store at 4° C
Melting Point :
219-221° C (lit.)
Fluoresence :
λex 485 nm, λem 501 nm in methanol
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
DM5285250
PubChem CID :
9894321
MDL Number :
MFCD00011954
EC Number :
264-899-3
Beilstein Registry :
9312562
SMILES :
CCCCCCN\\1C2=CC=CC=C2O/C1=C/C=C/C3=[N+](C4=CC=CC=C4O3)CCCCCC.[I-]

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Certificate of Analysis

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3,3prime-Dihexyloxacarbocyanine Iodide  Product Citations

See how others have used 3,3prime-Dihexyloxacarbocyanine Iodide. Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 23433093  Lin, CH. et al. 2013. BMC Complement Altern Med. 13: -.

PMID: # 22611426  Yang, JS. et al. 2012. Evid Based Complement Alternat Med. 2012: -.

PMID: # 22334654  Almeida, AS. et al. 2012. J. Biol. Chem. 287: 10761-10770.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from Great for Membrane staining in mouse Worked! 1:200 for WB on NIH/3T3 with 30min incubation. Used direct conjugate sc-324-AC
Date published: 2018-09-19
Rated 5 out of 5 by from Various publications cite the use of 3 Various publications cite the use of 3,3 -Dihexyloxacarbocyanine Iodide, a cationic, voltage-sensitive, cell-permeable, lipophilic, green fluorescent, carbocyanine dye, as a membrane potential probe. At a low concentration, the dye will selectively stain the mitochondria of live cells. At high concentrations the dye will stain the endoplasmic reticulum and other internal membranes. -SCBT Publication Review
Date published: 2015-07-15
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