Molecular structure of 3,3′,5-Triiodo-D-thyronine, CAS Number: 5714-08-9
3,3′,5-Triiodo-D-thyronine (CAS 5714-08-9)
Alternate Names:
D-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]alanine; (+)-Triiodothyronine; DT 3
CAS Number:
5714-08-9
Molecular Weight:
650.97
Molecular Formula:
C15H12I3NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3,3′,5-Triiodo-D-thyronine is a compound of interest in endocrinology research due to its structural similarity to thyroid hormones. It serves as a key molecule in studies exploring the regulation of metabolic pathways, as its incorporation into experimental setups allows scientists to observe alterations in metabolic rate and temperature homeostasis under controlled conditions. This analog is particularly valuable in molecular biology for probing the function of thyroid hormone receptors and elucidating their role in gene expression. In cellular research, 3,3′,5-Triiodo-D-thyronine is employed to investigate the intricacies of hormone transport across cell membranes, and its impact on cellular metabolism and energy production.
3,3′,5-Triiodo-D-thyronine (CAS 5714-08-9) References
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- Thyroid hormone stimulates phosphoglycerate mutase activity and isozyme transition in rat muscle tissues. | Esteller, M., et al. 1994. Life Sci. 54: 533-8. PMID: 8107530
- Analysis of the binding of 3,3',5-triiodo-L-thyronine and its analogues to mutant human beta 1 thyroid hormone receptors: a model of the hormone binding site. | Cheng, SY., et al. 1994. Biochemistry. 33: 4319-26. PMID: 8155649
- Triiodothyronine is a high-affinity inhibitor of amino acid transport system L1 in cultured astrocytes. | Blondeau, JP., et al. 1993. J Neurochem. 60: 1407-13. PMID: 8455031
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,3′,5-Triiodo-D-thyronine, 10 mg | sc-474189 | 10 mg | $398.00 | |||
3,3′,5-Triiodo-D-thyronine, 100 mg | sc-474189A | 100 mg | $2346.00 |