Molecular structure of 3,3-Dimethyl-1-butanol, CAS Number: 624-95-3
3,3-Dimethyl-1-butanol (CAS 624-95-3)
Alternate Names:
3,3-Dimethylbutanol
CAS Number:
624-95-3
Molecular Weight:
102.17
Molecular Formula:
C6H14O
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
3,3-Dimethyl-1-butanol is classified as a tertiary alcohol and exhibits solubility in various organic solvents. Its significance lies in serving as a model compound for researching alcohol metabolism. Scientists have utilized it to investigate the impact of environmental pollutants on organs like the liver, kidney, and others.
3,3-Dimethyl-1-butanol (CAS 624-95-3) References
- Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis. | Wang, Z., et al. 2015. Cell. 163: 1585-95. PMID: 26687352
- Gut Microbiota in Vascular Disease: Therapeutic Target? | Anbazhagan, AN., et al. 2017. Curr Vasc Pharmacol. 15: 291-295. PMID: 28056754
- Trimethylamine N-oxide (TMAO) as a New Potential Therapeutic Target for Insulin Resistance and Cancer. | Oellgaard, J., et al. 2017. Curr Pharm Des. 23: 3699-3712. PMID: 28641532
- 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice. | Wang, G., et al. 2020. J Nutr Biochem. 78: 108341. PMID: 32004931
- The gut microbial metabolite trimethylamine N-oxide aggravates GVHD by inducing M1 macrophage polarization in mice. | Wu, K., et al. 2020. Blood. 136: 501-515. PMID: 32291445
- Trimethylamine N-oxide impairs perfusion recovery after hindlimb ischemia. | Chen, L., et al. 2020. Biochem Biophys Res Commun. 530: 95-99. PMID: 32828321
- Repeated 3,3-Dimethyl-1-butanol exposure alters social dominance in adult mice. | Mao, J., et al. 2021. Neurosci Lett. 758: 136006. PMID: 34098029
- Trimethylamine N-oxide induces osteogenic responses in human aortic valve interstitial cells in vitro and aggravates aortic valve lesions in mice. | Li, J., et al. 2022. Cardiovasc Res. 118: 2018-2030. PMID: 34352088
- Maternal 3,3-Dimethyl-1-Butanol Therapy Protects Adult Male Rat Offspring against Hypertension Programmed by Perinatal TCDD Exposure. | Hsu, CN., et al. 2021. Nutrients. 13: PMID: 34578924
- Gut Microbial Metabolite Trimethylamine N-Oxide Aggravates Pulmonary Hypertension. | Huang, Y., et al. 2022. Am J Respir Cell Mol Biol. 66: 452-460. PMID: 35100519
- Inhibition of Trimethylamine N-Oxide Attenuates Neointimal Formation Through Reduction of Inflammasome and Oxidative Stress in a Mouse Model of Carotid Artery Ligation. | Chen, CY., et al. 2023. Antioxid Redox Signal. 38: 215-233. PMID: 35713239
- Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice. | Casso, AG., et al. 2022. J Physiol. 600: 4633-4651. PMID: 36111692
- Gut Microbiota and Coronary Artery Disease: Current Therapeutic Perspectives. | Katsimichas, T., et al. 2023. Metabolites. 13: PMID: 36837875
- Carbamylation and decarbamylation of acetylcholinesterase: effect of choline, 3,3-dimethyl-1-butanol and some allosteric effectors. | Dawson, RM. 1978. J Neurochem. 30: 865-70. PMID: 565804
- Silicon-substituted medicinal agents. Parasympatholytic activity of 3,3-dimethyl-1-butanol carbamate and 2-trimethylsilyl-1-ethanol carbamate. | Fessenden, RJ. and Rittenhouse, R. 1968. J Med Chem. 11: 1070-1. PMID: 5697075
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3,3-Dimethyl-1-butanol, 10 g | sc-238631 | 10 g | $88.00 | |||
3,3-Dimethyl-1-butanol, 50 g | sc-238631A | 50 g | $336.00 |