Molecular structure of 3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one, CAS Number: 40526-64-5
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one (CAS 40526-64-5)
Alternate Names:
3-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]-1H-indol-2-one
Application:
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one is a receptor tyrosine kinase inhibitor
CAS Number:
40526-64-5
Molecular Weight:
349.5
Molecular Formula:
C23H27NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Receptor tyrosine kinase (RTK) inhibitor. Inhibits FLK-1 RTK (IC50~8µM) and EGF RTK. Consists of the E- and Z-isomers [1].
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one (CAS 40526-64-5) References
- Synthesis and biological evaluations of 3-substituted indolin-2-ones: a novel class of tyrosine kinase inhibitors that exhibit selectivity toward particular receptor tyrosine kinases. | Sun, L., et al. 1998. J Med Chem. 41: 2588-603. PMID: 9651163
Inhibitor of:
Tyrosine Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one, 1 mg | sc-202015 | 1 mg | $35.00 | |||
3-(3,5-Di-tert-butyl-4-hydroxybenzylidenyl)indolin-2-one, 5 mg | sc-202015A | 5 mg | $137.00 |