Date published: 2026-4-30

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3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid (CAS 104582-29-8)

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Alternate Names:
3-[[2-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]ethyl]dithio]propanoic Acid;
Application:
3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid is used in the production of cleavable biotin-conjugated haptens
CAS Number:
104582-29-8
Molecular Weight:
407.57
Molecular Formula:
C15H25N3O4S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid is used in the production of cleavable biotin-conjugated haptens. 3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid undergoes a thiol-ene reaction to establish a covalent linkage with proteins and other molecules. The biotin component of the compound attaches to a particular protein or molecule, while the dithiopropionic acid part forms a stable covalent bond with a cysteine residue or another thiol group. This covalent bond is stable and can be used to study protein-protein interactions.


3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid (CAS 104582-29-8) References

  1. Dissociation-independent selection of high-affinity anti-hapten phage antibodies using cleavable biotin-conjugated haptens.  |  Kobayashi, N., et al. 2005. Anal Biochem. 347: 287-96. PMID: 16288966
  2. Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer.  |  Tailor, D., et al. 2021. Cell Chem Biol. 28: 1206-1220.e6. PMID: 33713600
  3. Studying the ubiquitin code through biotin-based labelling methods.  |  Barroso-Gomila, O., et al. 2022. Semin Cell Dev Biol. 132: 109-119. PMID: 35181195

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid, 10 mg

sc-206612A
10 mg
$151.00

3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid, 50 mg

sc-206612B
50 mg
$240.00

3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid, 100 mg

sc-206612
100 mg
$374.00