3-(2-Hydroxyphenyl)propionic acid (CAS 495-78-3)

3-(2-Hydroxyphenyl)propanoic acid, known as 3-hydroxybenzoic acid (3-HB) or protocatechuic acid (PCA), is an aromatic organic acid found in numerous plants and fruits. As a naturally occurring phenolic compound, it has garnered considerable attention for its diverse biological activities. Its applications extend to being used as a food preservative and antioxidant. Moreover, 3-(2-Hydroxyphenyl)propionic acid plays a role in the synthesis of various pharmaceuticals and other compounds. Despite its extensive study, the exact mechanism of action of 3-(2-Hydroxyphenyl)propionic acid remains somewhat enigmatic. Researchers believe that it may exert its effects by inhibiting several enzymes, including cyclooxygenase-2 (COX-2), lipoxygenase (LOX), and matrix metalloproteinase (MMP). Additionally, there are indications that it can also modulate the activity of specific transcription factors, such as nuclear factor kappa B (NF-κB). 3-(2-Hydroxyphenyl)propanoic acid, 3-hydroxybenzoic acid (3-HB), or protocatechuic acid (PCA) holds significant promise as a natural compound with a wide array of potential applications and intriguing biological actions, even though the precise mechanisms underlying its effects warrant further investigation.