Date published: 2026-5-3

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3-(2-Hydroxyethyl)indole (CAS 526-55-6)

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Application:
3-(2-Hydroxyethyl)indole is an indole for the production of compounds used in biological research
CAS Number:
526-55-6
Purity:
≥98%
Molecular Weight:
161.20
Molecular Formula:
C10H11NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-(2-Hydroxyethyl)indole is a substrate in various enzymatic reactions. It acts as a precursor in the synthesis of indole derivatives, which are important in the development of agrochemicals. 3-(2-Hydroxyethyl)Indole undergoes specific chemical transformations, leading to the formation of new molecular structures with potential biological activities. At the molecular level, 3-(2-Hydroxyethyl)indole interacts with enzymes and other chemical reagents to facilitate the production of diverse indole-based compounds.


3-(2-Hydroxyethyl)indole (CAS 526-55-6) References

  1. The pyruvate kinase of Stigmatella aurantiaca is an indole binding protein and essential for development.  |  Stamm, I., et al. 2005. Mol Microbiol. 56: 1386-95. PMID: 15882428
  2. N-carboxamido-staurosporine and selina-4(14),7(11)-diene-8,9-diol, new metabolites from a marine Streptomyces sp.  |  Wu, SJ., et al. 2006. J Antibiot (Tokyo). 59: 331-7. PMID: 16915816
  3. Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.  |  Adachi, H., et al. 2007. J Med Chem. 50: 1810-27. PMID: 17378544
  4. The L293 residue in transmembrane domain 2 of the 5-HT3A receptor is a molecular determinant of allosteric modulation by 5-hydroxyindole.  |  Hu, XQ. and Lovinger, DM. 2008. Neuropharmacology. 54: 1153-65. PMID: 18436267
  5. Which agonist properties are important for the activation of 5-HT3A receptors?  |  Meiboom, MF., et al. 2013. Biochim Biophys Acta. 1828: 2564-73. PMID: 23792067
  6. Polyphenols and Tryptophan Metabolites Activate the Aryl Hydrocarbon Receptor in an in vitro Model of Colonic Fermentation.  |  Koper, JEB., et al. 2019. Mol Nutr Food Res. 63: e1800722. PMID: 30443985
  7. XszenFHal, a novel tryptophan 5-halogenase from Xenorhabdus szentirmaii.  |  Domergue, J., et al. 2019. AMB Express. 9: 175. PMID: 31673806
  8. Bioconversion of Biologically Active Indole Derivatives with Indole-3-Acetic Acid-Degrading Enzymes from Caballeronia glathei DSM50014.  |  Sadauskas, M., et al. 2020. Biomolecules. 10: PMID: 32344740
  9. Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens.  |  Sethupathy, S., et al. 2020. Front Microbiol. 11: 584812. PMID: 33193228
  10. Metabolomic Expression of Laryngeal and Hindlimb Muscles in Adult versus Senescent Rats.  |  Shembel, AC., et al. 2022. Ann Otol Rhinol Laryngol. 131: 259-267. PMID: 34041924
  11. Liquid chromatography-tandem mass spectrometry analysis for identification and quantification of antimicrobial compounds in distillery wastewater.  |  Hou, W., et al. 2021. MethodsX. 8: 101470. PMID: 34430343
  12. Characteristics of Serum Metabolites and Gut Microbiota in Diabetic Kidney Disease.  |  Zhang, B., et al. 2022. Front Pharmacol. 13: 872988. PMID: 35548353
  13. Identifying potential biomarkers and therapeutic targets for dogs with sepsis using metabolomics and lipidomics analyses.  |  Montague, B., et al. 2022. PLoS One. 17: e0271137. PMID: 35802586
  14. Comparative Metagenomics and Metabolomes Reveals Abnormal Metabolism Activity Is Associated with Gut Microbiota in Alzheimer's Disease Mice.  |  Sun, P., et al. 2022. Int J Mol Sci. 23: PMID: 36232865
  15. Screening of Endophytic Bacteria of Leucojum aestivum 'Gravety Giant' as a Potential Source of Alkaloids and as Antagonist to Some Plant Fungal Pathogens.  |  Munakata, Y., et al. 2022. Microorganisms. 10: PMID: 36296365

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-(2-Hydroxyethyl)indole, 1 g

sc-256394A
1 g
$47.00

3-(2-Hydroxyethyl)indole, 5 g

sc-256394
5 g
$104.00

3-(2-Hydroxyethyl)indole, 25 g

sc-256394B
25 g
$349.00

3-(2-Hydroxyethyl)indole, 100 g

sc-256394C
100 g
$883.00