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![Molecular structure of 3-{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}-1-propanamine 3-{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}-1-propanamine - chemical structure image](https://media.scbt.com/product/3-2-3-fluoro-4-trifluoromethyl-phenyl-1-3-thiazol-4-yl-1-propanamine-structure_22_83_t_228379.jpg)
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Mevastatin (Compactin) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation. Mevastatin causes cells to arrest early in the G1 phase. Mevastatin is a close structural analog of lovastatin (sc-200850) and both agents have the same biochemical activities. Mevastatin is inactive in cell-free assays. In cells however, it is hydrolyzed to the active free acid form by intracellular esterases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}-1-propanamine, 500 mg | sc-312228 | 500 mg | $492.00 | |||
3-{2-[3-Fluoro-4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}-1-propanamine, 1 g | sc-312228A | 1 g | $670.00 |