Date published: 2025-10-14

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3,17β-O-Bis(methoxymethyl)estradiol (CAS 113680-55-0)

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CAS Number:
113680-55-0
Molecular Weight:
360.49
Molecular Formula:
C22H32O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3,17β-O-Bis(methoxymethyl)estradiol (CAS 113680-55-0) References

  1. Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.  |  Wang, Z., et al. 2000. J Med Chem. 43: 2419-29. PMID: 10882369
  2. 2ME2 inhibits tumor growth and angiogenesis by disrupting microtubules and dysregulating HIF.  |  Mabjeesh, NJ., et al. 2003. Cancer Cell. 3: 363-75. PMID: 12726862
  3. Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol.  |  Klauber, N., et al. 1997. Cancer Res. 57: 81-6. PMID: 8988045
  4. The antiproliferative agent didemnin B uncompetitively inhibits palmitoyl protein thioesterase.  |  Meng, L., et al. 1998. Biochemistry. 37: 10488-92. PMID: 9671519
  5. Synthesis of 2‐[11C] methoxy‐3, 17β‐estradiol to measure the pharmacokinetics of an antitumor drug candidate, 2‐methoxy‐3, 17β‐estradiol  |  Mun, J., Voll, R. J., & Goodman, M. M. 2006. Journal of Labelled Compounds and Radiopharmaceuticals: The Official Journal of the International Isotope Society. 49(12): 1117-1124.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3,17β-O-Bis(methoxymethyl)estradiol, 250 mg

sc-209684
250 mg
$320.00