![3-[(E)-2-Phenylvinyl]-1H-pyrazole-4-carbaldehyde - chemical structure image](https://media.scbt.com/product/3--e-2-phenylvinyl-1h-pyrazole-4-carbaldehyde-structure_33_56_b_335672.jpg)
![Molecular structure of 3-[(E)-2-Phenylvinyl]-1H-pyrazole-4-carbaldehyde 3-[(E)-2-Phenylvinyl]-1H-pyrazole-4-carbaldehyde - chemical structure image](https://media.scbt.com/product/3--e-2-phenylvinyl-1h-pyrazole-4-carbaldehyde-structure_33_56_t_335672.jpg)
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PKI (5-24), PKA Inhibitor is a potent, competitive, synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) derived from the active domain of the naturally-occurring heat-stable inhibitor protein PKI. This pseudosubstrate inhibitor peptide mimics the protein substrate by binding to the catalytic site via the arginine-cluster basic subsite, which provides high specificity. PKA catalytic subunit residues Tyr235 and Phe239 form a sandwich-like structure with residue Phe10 of PKI (5-24), PKA Inhibitor this is a prominent enzyme-substrate interaction site. PKI (5-24), PKA Inhibitor exhibits a Ki of 2.3 nM with respect to PKA and is an extremely weak inhibitor of cGMP-dependent protein kinase (PKG).
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(E)-2-Phenylvinyl]-1H-pyrazole-4-carbaldehyde, 500 mg | sc-310584 | 500 mg | $270.00 |