![3-[(5-Methyl-furan-2-carbonyl)-amino]-benzoic acid - chemical structure image](https://media.scbt.com/product/3--5-methyl-furan-2-carbonyl-amino-benzoic-acid-structure_22_68_b_226871.jpg)
![3-[(5-Methyl-furan-2-carbonyl)-amino]-benzoic acid - chemical structure image](https://media.scbt.com/product/3--5-methyl-furan-2-carbonyl-amino-benzoic-acid-structure_22_68_t_226871.jpg "Molecular structure of 3-[(5-Methyl-furan-2-carbonyl)-amino]-benzoic acid")
3-[(5-Methyl-furan-2-carbonyl)-amino]-benzoic acid
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Triptolide is a diterpene triepoxide antibiotic originally isolated from extracts of the herb Tripterygium wilfordii Hook F (TWHF). Triptolide may act to induce apoptosis of T lymphocytes by activating caspases, displaying an increase of DEVD-cleavable caspase activity correlated with the apoptosis. The proliferation of rheumatoid synovial fibroblasts characteristic of rheumatoid arthritis was similarly suppressed by treatment with Triptolide through an increase in caspase-3 activity. Cytokine gene expression in blood lymphocytes and T-cells are also suppressed by Triptolide, blocking the transcriptional activation of purine-box/antigen receptor response element/nuclear factor of activated T-cells (NF-AT) and of NF-kappaB.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(5-Methyl-furan-2-carbonyl)-amino]-benzoic acid, 500 mg | sc-310569 | 500 mg | $240.00 |