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Proadifen hydrochloride also known as SKF-525A HCl has many biochemical functions, some of which include: inhibitory effects on NOS1 (neuronal nitric oxide synthase IC50 = 90 mM), adult mouse skeletal muscle AChR (acetyl choline receptor), hepatic drug metabolism via the CYP (cytochrome P450) system, CYP-dependent (cytochrome P450-dependent) arachidonate metabolism (90% at 50 muM), transmembrane calcium influx, and platelet thromboxane synthesis. This compound has also been shown to block KIR6.1 (ATP-sensitive inward rectifier potassium channel 8 IC50 = 4.4 mM) and stimulate endothelial cell prostacyclin production.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(5-Bromo-2-pyrimidinyl)oxy]benzenecarbaldehyde, 500 mg | sc-310563 | 500 mg | $492.00 | |||
3-[(5-Bromo-2-pyrimidinyl)oxy]benzenecarbaldehyde, 1 g | sc-310563A | 1 g | $670.00 |