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Aprotinin is a single chain polypeptide (58 amino-acids) crosslinked by three disulfide bridges, showing competitive and reversible inhibiton of proteolytic and esterolytic activity. Aprotinin forms stable complexes and blocks the active sites of serine protease enzymes. Binding is reversible with most aprotinin-protease complexes dissociating at pH >10 or < 3 (optimum pH 5-7) effective concentration is equimolar with protease. Aprotinin is used as a proteolytic inhibitor in radioimmunoassays of polypeptide hormones. Aprotinin can also be a competitive inhibitor of nNOS and iNOS with Ki values of 50 and 78uM.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(4-Methylbenzyl)oxy]-2-thiophenecarboxylic acid, 500 mg | sc-310546 | 500 mg | $146.00 | |||
3-[(4-Methylbenzyl)oxy]-2-thiophenecarboxylic acid, 1 g | sc-310546A | 1 g | $203.00 |