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Concanamycin A is a compound that is primarily utilized for research into cellular autophagy and V-ATPase inhibition. It acts by specifically inhibiting the vacuolar-type H+-ATPase (V-ATPase) proton pump, which is essential for acidifying intracellular compartments in eukaryotic cells. This action makes concanamycin A useful in examining the acidification of endosomes, lysosomes, and the Golgi apparatus. Researchers also use this compound to study the mechanisms of intracellular protein degradation, as V-ATPase activity is for the function of the lysosome, a central organelle in the autophagic process. Additionally, concanamycin A is of interest in investigations of ion homeostasis and membrane trafficking due to its influence on cellular pH gradients.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(4-Isopropylphenoxy)methyl]piperidine, 500 mg | sc-310538 | 500 mg | $294.00 |