![3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid - chemical structure image](https://media.scbt.com/product/3--4-hydroxypiperidin-1-yl-carbonyl-2-2-dimethylcyclopropanecarboxylic-acid-structure_22_68_b_226842.jpg)
![3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid - chemical structure image](https://media.scbt.com/product/3--4-hydroxypiperidin-1-yl-carbonyl-2-2-dimethylcyclopropanecarboxylic-acid-structure_22_68_t_226842.jpg "Molecular structure of 3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid")
3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid
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Autophagy Inhibitor, 3-MA is a synthetic intermediate and a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis post serum/potassium deprivation. It is a PI 3-kinase p100 (class III PI 3-kinase inhibitor) that displays distinctly different properties from the PI 3-kinase inhibitors LY 294002 (sc-201426) and Wortmannin (sc-3505), in that treatment of cells with Autophagy Inhibitor, 3-MA results in specific redistribution of mannose 6-phosphate/insulin-like growth factor II receptor (MPR300), but does not cause the enlargement of late endosomal/lysosomal compartments. Autophagy Inhibitor, 3-MA is also an inhibitor of PI 3-kinase p110 gamma. Autophagy Inhibitor, 3-MA is also known as 3-methyladenine, 3-methyladenine inhibitor, 3-MA, and 6-Amino-3-methylpurine.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(4-Hydroxypiperidin-1-yl)carbonyl]-2,2-dimethylcyclopropanecarboxylic acid, 500 mg | sc-310535 | 500 mg | $270.00 |