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Apigenin is an antioxidant plant flavanoid which contains anti-inflammatory and anticancer properties. Apigenin may induce apoptosis and may inhibit proliferation of tumor cells by arresting the cell cycle at the G2/M phase. Apigenin is also known to be a MAP kinase inhibitor and a selective inhibitor of Protein Kinase 2 (CK2). Apigenin is capable of exerting diverse effects on a vast variety of molecular targets. Most effects of Apigenin appear to be mostly mediated through suppressing nitric oxide synthase-2 (NOS2), Hypoxia-inducible factor 1 alpha (HIF-1 alpha), lipoxygenase, cyclooxygenase-2 (COX-2) and vascular endothelial growth factor (VEGF) expression. Apigenin blocks proliferation of Wnt-1 transfected cells, dephosphorylates beta-catenin and lowers levels of beta-catenin and Dvi.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(4-Bromo-2-methylphenoxy)methyl]piperidine, 500 mg | sc-310491 | 500 mg | $294.00 |