![3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid (CAS 387350-58-5) - chemical structure image](https://media.scbt.com/product/3--4-6-dimethoxypyrimidin-2-yl-oxybenzoic-acid-387350-58-5-structure_22_82_b_228269.jpg)
![Molecular structure of 3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid, CAS Number: 387350-58-5 3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid (CAS 387350-58-5) - chemical structure image](https://media.scbt.com/product/3--4-6-dimethoxypyrimidin-2-yl-oxybenzoic-acid-387350-58-5-structure_22_82_t_228269.jpg)
QUICK LINKS
DAPT is a potent and specific inhibitor of gamma-secretase. It may act to cause a reduction in Abeta40 and Abeta42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Abeta40 and Abeta42 respectively). There is evidence that DAPT does not effect APPalpha and APPbeta levels. It mimics notch signaling deficiencies at morphological, molecular and biochemical levels and may act to block notch signaling in hybrid human-mouse foetal thymus organ culture (FTOC).
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid, 500 mg | sc-312106 | 500 mg | $98.00 |