Date published: 2026-9-3

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3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid (CAS 387350-58-5)

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CAS Number:
387350-58-5
Molecular Weight:
276.24
Molecular Formula:
C13H12N2O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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DAPT is a potent and specific inhibitor of gamma-secretase. It may act to cause a reduction in Abeta40 and Abeta42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Abeta40 and Abeta42 respectively). There is evidence that DAPT does not effect APPalpha and APPbeta levels. It mimics notch signaling deficiencies at morphological, molecular and biochemical levels and may act to block notch signaling in hybrid human-mouse foetal thymus organ culture (FTOC).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-[(4,6-Dimethoxypyrimidin-2-yl)oxy]benzoic acid, 500 mg

sc-312106
500 mg
$98.00