![3-[(2-Bromoacetyl)amino]-N-(1-phenylethyl)-benzamide - chemical structure image](https://media.scbt.com/product/3--2-bromoacetyl-amino-n-1-phenylethyl-benzamide-structure_22_67_b_226746.jpg)
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The most used form of nutlin, Nutlin-3 inhibits p53-Mdm2 interaction and the growth of human tumor xenografts in nude mice. Nutlin-3 has shown to induce the expression of p53-regulated genes and exhibits potent antiproliferative activity in cells with functional p53, but not in cells with mutated p53. When Nutlin-3 is in combination with perifosine, anti-leukaemic activity has been observed. High N-Myc (N-Myc) expression has been induced in non-N-MYC-amplified neuroblastoma cells when treated with the combination of Nutlin-3 and doxorubicin (sc-200923).
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-[(2-Bromoacetyl)amino]-N-(1-phenylethyl)-benzamide, 500 mg | sc-310423 | 500 mg | $284.00 |