(2S)-(+)-Amino-5-iodoacetamidopentanoic acid CAS: 35748-65-3
MF: C7H13N2O3I
MW: 300.09
An irreversible arginase inhibitor.

(2S)-(+)-Amino-5-iodoacetamidopentanoic acid (CAS 35748-65-3)

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Alternate Names: AIAP
Application: (2S)-(+)-Amino-5-iodoacetamidopentanoic acid is an irreversible arginase inhibitor
CAS Number: 35748-65-3
Molecular Weight: 300.09
Molecular Formula: C7H13N2O3I
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

(2S)-(+)-Amino-5-iodoacetamidopentanoic acid, also known as 2-AIPA, is an irreversible inhibitor of ODC (ornithine decarboxylase) and arginase. Both (2S)-(+)-Amino-5-iodoacetamidopentanoic acid and (2S)-(+)-Amino-6-iodoacetamidohexanoic acid (sc-220847) are demonstrated to produce antitumor effects in rat and mice studies, decreasing total serum proteins and increasing ALT and AST levels in these models.


References

1. Trujillo-Ferrara, J., et al. 1992. Cancer Lett. 67: 193-197. PMID: 1483267
2. Moroz, L.L., et al. 1996. J. Neurochem. 66: 873-876. PMID: 8592165
3. Massmann, G.A., et al. 1999. Am. J. Obstet. Gynecol. 181: 116-125. PMID: 10411806

Physical State :
Solid
Solubility :
Soluble in water (partly), and 6N aq. HCl.
Storage :
Store at -20° C
Melting Point :
301.48° C (Predicted)
Boiling Point :
~498.2° C at 760 mmHg (Predicted)
Density :
~1.8 g/cm3 (Predicted)
Refractive Index :
n20D 1.58 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
160253
MDL Number :
MFCD00278817
SMILES :
C(C[[email protected]@H](C(=O)O)N)CNC(=O)CI

Download SDS (MSDS)

Certificate of Analysis

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