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2′-Hydroxy-4′,6′-dimethoxyacetophenone (CAS 90-24-4)

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Alternate Names:
Xanthoxylin; Brevifolin; 1-(2-Hydroxy-4,6-dimethoxyphenyl)ethanone
Application:
2′-Hydroxy-4′,6′-dimethoxyacetophenone is a chemical with potential antibacterial agent effects and urease inhibitory effects as well as synthesis applications
CAS Number:
90-24-4
Molecular Weight:
196.20
Molecular Formula:
C10H12O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2′-Hydroxy-4′,6′-dimethoxyacetophenone, a compound commonly found in various plant species, has drawn considerable interest in scientific research for its diverse biological activities and potential applications. This chemical exhibits significant antioxidant properties due to its ability to scavenge free radicals and prevent oxidative damage to cellular components. Additionally, studies have shown that it possesses anti-inflammatory effects by inhibiting pro-inflammatory cytokines and enzymes involved in the inflammatory process, thereby attenuating inflammatory responses. Furthermore, 2′-Hydroxy-4′,6′-dimethoxyacetophenone has demonstrated promising anticancer properties by inducing apoptosis in cancer cells through multiple pathways, including the activation of caspases and modulation of cell cycle progression. Its ability to inhibit angiogenesis, the formation of new blood vessels crucial for tumor growth and metastasis, further enhances its potential as an agent against cancer. Moreover, research has explored its antimicrobial activity against various pathogens, suggesting its potential as a natural antimicrobial agent for combating microbial infections. Overall, the multifaceted biological activities of 2′-Hydroxy-4′,6′-dimethoxyacetophenone make it a promising candidate for further investigation in various research areas, including antioxidant therapy, anti-inflammatory treatment, cancer therapy, and antimicrobial drug development.


2′-Hydroxy-4′,6′-dimethoxyacetophenone (CAS 90-24-4) References

  1. Action of 2-hydroxy-4,6-dimethoxyacetophenone isolated from Sebastiania schottiana.  |  Calixto, JB., et al. 1990. Planta Med. 56: 31-5. PMID: 2356240
  2. Synthesis, photoluminescence and biological properties of terbium(III) complexes with hydroxyketone and nitrogen containing heterocyclic ligands.  |  Poonam,., et al. 2016. Spectrochim Acta A Mol Biomol Spectrosc. 152: 304-10. PMID: 26232573
  3. Antifungal hydroxy-acetophenones from the New Zealand liverwort, Plagiochila fasciculata.  |  Lorimer, SD. and Perry, NB. 1994. Planta Med. 60: 386-7. PMID: 7938276
  4. Constituents from the stem wood of Euphorbia quinquecostata with phorbol dibutyrate receptor-binding inhibitory activity.  |  Mbwambo, ZH., et al. 1996. J Nat Prod. 59: 1051-5. PMID: 8946746
  5. 2-Hydroxy-4, 6-dimethoxyacetophenone from leaves of Peperomia glabella[J].  |  Soares M G, de Felippe A P V, Guimarães E F. 2006,. Journal of the Brazilian Chemical Society,. 17:: 1205-1210.
  6. Synthesis and characterization some flavonoids derivatives[J].  |  AHMAD F, IDRIS M S U M H J, ADIB A M. 2006,. Research vote,. 75148.
  7. Luminescent properties of europium and terbium complexes with 2′-hydroxy-4′, 6′-dimethoxyacetophenone[J].  |  Taxak V B, Kumar R, Makrandi J K., 2010,. Displays. 31(3):: 116-121.
  8. Modified syntheses of the dietary flavonoid luteolin[J].  |  Wang Q, Zhang J, Liu M,. 2015,. Journal of Chemical Research,. 39(9):: 550-552.
  9. Antifungal activity and synergistic effect of acetophenones isolated from species Croton against dermatophytes and yeasts[J].  |  de Aguiar F L L, de Morais S M, Albuquerque M R J R. 2016,. Journal of Medicinal Plants Research,. 10(17):: 216-222.
  10. Chalcones and flavanones bearing hydroxyl and/or methoxyl groups: Synthesis and biological assessments[J].  |  Rosa G P, Seca A M L, Barreto M C,. 2019,. Applied Sciences,. 9(14):: 2846.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2'-Hydroxy-4',6'-dimethoxyacetophenone, 5 g

sc-254389
5 g
$149.00