Date published: 2026-4-11

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2′-Fucosyl-D-lactose (CAS 41263-94-9)

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Application:
2′-Fucosyl-D-lactose is a substrate used to identify, differentiate and characterized fucosidases
CAS Number:
41263-94-9
Purity:
≥95%
Molecular Weight:
488.44
Molecular Formula:
C18H32O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2′-Fucosyl-D-lactose is a compound that functions as a specific substrate for fucosidases in enzymatic studies. It serves as a model compound for investigating the enzymatic hydrolysis of fucosylated oligosaccharides. The mechanism of action involves the interaction of 2′-Fucosyl-D-lactose with fucosidase enzymes, leading to the cleavage of the fucosyl linkage and the release of fucose and lactose moieties. 2′-Fucosyl-D-lactose is utilized to study the kinetics and specificity of fucosidase enzymes, providing insights into their substrate preferences and catalytic mechanisms. In experimental applications, 2′-Fucosyl-D-lactose is used to understand the molecular interactions between fucosidases and fucosylated substrates, contributing to the analysis of carbohydrate metabolism and glycoside hydrolase enzymes. Its role in enzymatic studies allows for the investigation of fucose-containing oligosaccharides and their enzymatic degradation, providing useful information for carbohydrate biochemistry research.


2′-Fucosyl-D-lactose (CAS 41263-94-9) References

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  2. Fucosylated glycan inhibition of human hepatocellular carcinoma cell migration through binding to chemokine receptors.  |  Wu, LH., et al. 2010. Glycobiology. 20: 215-23. PMID: 19884117
  3. Determination and quantification of 2'-O-fucosyllactose and 3-O-fucosyllactose in human milk by GC-MS as O-trimethylsilyl-oxime derivatives.  |  Balogh, R., et al. 2015. J Pharm Biomed Anal. 115: 450-6. PMID: 26291789
  4. UV-activated multilayer nanomatrix provides one-step tunable carbohydrate structural characterization in MALDI-MS.  |  Obena, RP., et al. 2015. Chem Sci. 6: 4790-4800. PMID: 28717486
  5. Safety assessment of biotechnologically produced 2'-Fucosyllactose, a novel food additive.  |  van Berlo, D., et al. 2018. Food Chem Toxicol. 118: 84-93. PMID: 29704579
  6. Synthesis of Fucose-Containing Disaccharides by Glycosylhydrolases from Various Origins.  |  Alatorre-Santamaría, S., et al. 2019. Appl Biochem Biotechnol. 188: 369-380. PMID: 30467689
  7. Human Milk Oligosaccharide Supplementation Affects Intestinal Barrier Function and Microbial Composition in the Gastrointestinal Tract of Young Sprague Dawley Rats.  |  Chleilat, F., et al. 2020. Nutrients. 12: PMID: 32466125
  8. Safety of 2'-fucosyllactose (2'-FL) produced by a derivative strain (APC199) of Corynebacterium glutamicumATCC 13032 as a novel food pursuant to Regulation (EU) 2015/2283.  |  , ., et al. 2022. EFSA J. 20: e07647. PMID: 36531695
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  10. Minimizing acetate formation from overflow metabolism in Escherichia coli: comparison of genetic engineering strategies to improve robustness toward sugar gradients in large-scale fermentation processes.  |  Gecse, G., et al. 2024. Front Bioeng Biotechnol. 12: 1339054. PMID: 38419731

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2′-Fucosyl-D-lactose, 1 mg

sc-256371
1 mg
$204.00