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2′-Deoxyadenosine monohydrate (CAS 16373-93-6)

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Alternate Names:
9-(2-Deoxy-β-D-ribofuranosyl)adenine; Adenine deoxyriboside
Application:
2′-Deoxyadenosine monohydrate is a deoxyribonucleoside
CAS Number:
16373-93-6
Molecular Weight:
269.26
Molecular Formula:
C10H13N5O3•H2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2′-Deoxyadenosine monohydrate may affect cAMP levels in some cells. It also may be used as an energy source by some cells under energy stress conditions. 2′-Deoxyadenosine monohydrate can be used in the synthesis of 5′-modified 2′-deoxyadenosine analogues.


2′-Deoxyadenosine monohydrate (CAS 16373-93-6) References

  1. Synthesis of two 8-[(anthraquinone-2-yl)-linked]-2'-deoxyadenosine 3'-benzyl hydrogen phosphates for studies of photoinduced hole transport in DNA.  |  Abou-Elkhair, RA. and Netzel, TL. 2005. Nucleosides Nucleotides Nucleic Acids. 24: 85-110. PMID: 15822616
  2. N6-Arylation of 2'-deoxyadenosine via copper-catalyzed direct coupling with aryl halides.  |  Ran, C., et al. 2005. J Org Chem. 70: 3724-6. PMID: 15845015
  3. Increasing surface enhanced Raman spectroscopy effect of RNA and DNA components by changing the pH of silver colloidal suspensions.  |  Primera-Pedrozo, OM., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 87: 77-85. PMID: 22169024
  4. Purine 5',8-cyclo-2'-deoxynucleoside lesions: formation by radical stress and repair in human breast epithelial cancer cells.  |  Krokidis, MG., et al. 2017. Free Radic Res. 51: 470-482. PMID: 28463089
  5. Proton Transfer Accompanied by the Oxidation of Adenosine.  |  Choi, J., et al. 2019. Chemistry. 25: 7711-7718. PMID: 30957282
  6. Increased levels of 5',8-Cyclopurine DNA lesions in inflammatory bowel diseases.  |  Masi, A., et al. 2020. Redox Biol. 34: 101562. PMID: 32413746
  7. Proteomics and metabolomics analysis reveal potential mechanism of extended-spectrum β-lactamase production in Escherichia coli.  |  Ma, H., et al. 2020. RSC Adv. 10: 26862-26873. PMID: 35515772
  8. Purine nucleosides. XI. The synthesis of 2'-deoxy-9-alpha- and-beta-D-ribofuranosylpurines and the correlation of their anomeric structure with proton magnetic resonance spectra.  |  Robins, MJ. and Robins, RK. 1965. J Am Chem Soc. 87: 4934-40. PMID: 5844465
  9. Synchronization of DNA synthesis in Neurospora crassa by 2'-deoxyadenosine and spore selection.  |  Fletcher, MH. and Trinci, AP. 1980. Arch Microbiol. 128: 113-9. PMID: 6450576
  10. Chemistry of muconaldehydes of possible relevance to the toxicology of benzene.  |  Bleasdale, C., et al. 1996. Environ Health Perspect. 104 Suppl 6: 1201-9. PMID: 9118894
  11. Influence of crystal packing on the solid-state desolvation of purine and pyrimidine hydrates: loss of water of crystallization from thymine monohydrate, cytosine monohydrate, 5-nitrouracil monohydrate, and 2'-deoxyadenosine monohydrate  |  Perrier, P., & Byrn, S. R. 1982. The Journal of Organic Chemistry. 47(24): 4671-4676.
  12. Palladium catalysis in the synthesis of 8-position modified adenosine, 2′-deoxyadenosine and guanosine  |  Tu, C., Keane, C., & Eaton, B. E. 1995. Nucleosides, Nucleotides & Nucleic Acids. 14(8): 1631-1638.
  13. ibrational modes of nucleoside deoxyadenosine monohydrate investigated under high pressure.  |  Quimbayo, J. S., Lima, R. A., Vasconcelos, D. L., & Freire, P. T. 2020. Spectroscopy. 110: 103140.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2′-Deoxyadenosine monohydrate, 250 mg

sc-216290
250 mg
$31.00

2′-Deoxyadenosine monohydrate, 1 g

sc-216290A
1 g
$46.00