Molecular structure of 2′-Deoxyadenosine 5′-monophosphate, CAS Number: 653-63-4
2′-Deoxyadenosine 5′-monophosphate (CAS 653-63-4)
Alternate Names:
dAMP; 2′-Deoxy-5′-AMP
Application:
2′-Deoxyadenosine 5′-monophosphate is used to study adenosine-based cellular interactions
CAS Number:
653-63-4
Purity:
≥98%
Molecular Weight:
331.22
Molecular Formula:
C10H14N5O6P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2′-Deoxyadenosine-5′-monophosphate (dAMP or 2′-Deoxy-5′-AMP) is a derivative of the nucleic acid, AMP, in which the hydroxyl group on the 2′ carbon of the pentose has been reduced to a hydrogen atom. 2′-Deoxyadenosine-5′-monophosphate has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.
2′-Deoxyadenosine 5′-monophosphate (CAS 653-63-4) References
- Two novel dATP analogs for DNA photoaffinity labeling. | Zofall, M. and Bartholomew, B. 2000. Nucleic Acids Res. 28: 4382-90. PMID: 11058139
- Fast repairing of oxidized OH radical adducts of dAMP and dGMP by phenylpropanoid glycosides from Scrophularia ningpoensis Hemsl. | Li, YM., et al. 2000. Acta Pharmacol Sin. 21: 1125-8. PMID: 11603287
- Photosensitization of 2'-deoxyadenosine-5'-monophosphate by pterin. | Petroselli, G., et al. 2007. Org Biomol Chem. 5: 2792-9. PMID: 17700847
- Photosensitized electron transfer within a self-assembled norharmane-2'-deoxyadenosine 5'-monophosphate (dAMP) complex. | Gonzalez, MM., et al. 2012. Org Biomol Chem. 10: 9359-72. PMID: 23111419
- N3 Protonation Induces Base Rotation of 2'-Deoxyadenosine-5'-monophosphate and Adenosine-5'-monophosphate. | Wu, RR., et al. 2016. J Phys Chem B. 120: 4616-24. PMID: 27138137
- Direct Damage of Deoxyadenosine Monophosphate by Low-Energy Electrons Probed by X-ray Photoelectron Spectroscopy. | Kundu, S., et al. 2020. J Phys Chem B. 124: 1585-1591. PMID: 32043891
- Human and bacterial TatD enzymes exhibit apurinic/apyrimidinic (AP) endonuclease activity. | Dorival, J. and Eichman, BF. 2023. Nucleic Acids Res. 51: 2838-2849. PMID: 36881763
- OH Radical-Induced Oxidation in Nucleosides and Nucleotides Unraveled by Tandem Mass Spectrometry and Infrared Multiple Photon Dissociation Spectroscopy. | Jiang, Y., et al. 2023. Chemphyschem. 24: e202300534. PMID: 37713246
- Discovery and substrate specificity engineering of nucleotide halogenases. | Ni, J., et al. 2024. Nat Commun. 15: 5254. PMID: 38898020
- Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. | Duarte, V., et al. 1999. Nucleic Acids Res. 27: 496-502. PMID: 9862971
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′-Deoxyadenosine 5′-monophosphate, 100 mg | sc-216289 | 100 mg | $61.00 | |||
2′-Deoxyadenosine 5′-monophosphate, 500 mg | sc-216289A | 500 mg | $117.00 |