2′-Deoxy-β-L-adenosine (CAS 14365-45-8)
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2′-Deoxy-β-L-adenosine is a nucleoside analog that is structurally related to the naturally occurring nucleosides found in DNA. It represents an atypical configuration, as most naturally occurring nucleosides are in the ′D′ form. This compound is particularly useful in the field of molecular biology where it is used to study the structural requirements for the binding and incorporation of nucleotide analogs by enzymes such as polymerases and nucleases. Its presence in experimental applications can help elucidate the mechanisms of mutation, replication fidelity, and enzyme specificity. Additionally, 2′-Deoxy-β-L-adenosine is involved in research focusing on the development of nucleic acid-based probes, as the L-configuration can confer novel properties such as increased stability to enzymatic degradation.
2′-Deoxy-β-L-adenosine (CAS 14365-45-8) References
- Synthesis and physicochemical properties of oligonucleotides built with either alpha-L or beta-L nucleotides units and covalently linked to an acridine derivative. | Asseline, U., et al. 1991. Nucleic Acids Res. 19: 4067-74. PMID: 1651474
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′-Deoxy-β-L-adenosine, 100 mg | sc-220817 | 100 mg | $508.00 |