Molecular structure of 2′-Deoxy-2′-fluoroguanosine, CAS Number: 125291-17-0
2′-Deoxy-2′-fluoroguanosine (CAS 125291-17-0)
Alternate Names:
2'-Fluoro-2'-deoxy-D-guanosine; 2'-Fluoro-2'-deoxyguanosine
Application:
2′-Deoxy-2′-fluoroguanosine is a highly active antiviral agent
CAS Number:
125291-17-0
Purity:
≥99%
Molecular Weight:
285.23
Molecular Formula:
C10H12FN5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
2′-Deoxy-2′-fluoroguanosine is a highly active antiviral agent.
2′-Deoxy-2′-fluoroguanosine (CAS 125291-17-0) References
- Chemical and enzymatic synthesis and antiviral properties of 2'-deoxy-2'-fluoroguanosine. | Zaitseva, GV., et al. 1999. Nucleosides Nucleotides. 18: 687-8. PMID: 10432666
- [Antiviral activity of 2'-deoxy-2'-fluoroguanosine against influenza and herpes simplex viruses in cultured cells]. | Boreko, I., et al. 2001. Vopr Virusol. 46: 40-2. PMID: 11715709
- Synthesis and biological evaluation of purine 2'-fluoro-2'-deoxyriboside ProTides as anti-influenza virus agents. | Meneghesso, S., et al. 2013. ChemMedChem. 8: 415-25. PMID: 23386468
- Structures and Relative Glycosidic Bond Stabilities of Protonated 2'-Fluoro-Substituted Purine Nucleosides. | Devereaux, ZJ., et al. 2019. J Am Soc Mass Spectrom. 30: 1521-1536. PMID: 31111413
- Recognition by restriction endonuclease EcoRI of deoxyoctanucleotides containing modified sugar moieties. | Ohtsuka, E., et al. 1984. Eur J Biochem. 139: 447-50. PMID: 6321178
- Efficacy of 2'-deoxy-2'-fluororibosides against influenza A and B viruses in ferrets. | Jakeman, KJ., et al. 1994. Antimicrob Agents Chemother. 38: 1864-7. PMID: 7986023
- Comparative anti-influenza virus activity of 2'-deoxy-2'-fluororibosides in vitro. | Rollins, BS., et al. 1993. Antiviral Res. 21: 357-68. PMID: 8215305
- Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. | Tuttle, JV., et al. 1993. J Med Chem. 36: 119-25. PMID: 8421277
- Inhibition of influenza virus transcription by 2'-deoxy-2'-fluoroguanosine. | Tisdale, M., et al. 1995. Antimicrob Agents Chemother. 39: 2454-8. PMID: 8585725
- Effects of 2'-substituents of the first deoxyguanosine residue in the recognition sequence of EcoRI restriction endonuclease activity. | Gohda, K., et al. 1997. J Biochem. 121: 219-24. PMID: 9089393
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′-Deoxy-2′-fluoroguanosine, 50 mg | sc-283470 | 50 mg | $140.00 | |||
2′-Deoxy-2′-fluoroguanosine, 100 mg | sc-283470A | 100 mg | $220.00 |