Date published: 2025-9-26

1-800-457-3801

SCBT Portrait Logo
Seach Input

2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt (CAS 76204-02-9)

0.0(0)
Write a reviewAsk a question

Alternate Names:
4-Methylumbelliferyl-N-acetyl-α-D-neuraminic acid sodium salt
Application:
2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt is a substrate for fluorometric assay of neuraminidase
CAS Number:
76204-02-9
Purity:
≥95%
Molecular Weight:
489.41
Molecular Formula:
C21H24NO11•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt (2-MU-α-D-NANA) is a substrate for fluorometric assay of neuraminidase. It is also used for fluorescent staining of sialidases in polyacrylamide gel electrophoresis and as an affinity reagent in affinity chromatography. 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt is a sialic acid derivative, which is a type of sugar found in glycoproteins and glycolipids. It is a component of the glycocalyx, the outermost layer of cells, and is known to play a role in many biological processes, including cell adhesion and recognition, signal transduction, and inflammation.


2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt (CAS 76204-02-9) References

  1. Screening and identification of inhibitors against influenza A virus from a US drug collection of 1280 drugs.  |  An, L., et al. 2014. Antiviral Res. 109: 54-63. PMID: 24971493
  2. Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1.  |  Chen, GY., et al. 2014. Elife. 3: e04066. PMID: 25187624
  3. Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome.  |  Kim, JH., et al. 2014. Bioorg Med Chem. 22: 6047-52. PMID: 25277281
  4. Anti-Hemagglutinin Antibody Derived Lead Peptides for Inhibitors of Influenza Virus Binding.  |  Memczak, H., et al. 2016. PLoS One. 11: e0159074. PMID: 27415624
  5. Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.  |  Zhang, J., et al. 2018. J Med Chem. 61: 6379-6397. PMID: 29965752
  6. A structure-based rationale for sialic acid independent host-cell entry of Sosuga virus.  |  Stelfox, AJ. and Bowden, TA. 2019. Proc Natl Acad Sci U S A. 116: 21514-21520. PMID: 31591233
  7. Discovery of Multitarget-Directed Ligands Against Influenza A Virus From Compound Yizhihao Through a Predictive System for Compound-Protein Interactions.  |  Xu, L., et al. 2020. Front Cell Infect Microbiol. 10: 16. PMID: 32117796
  8. [Method for evaluating the neuraminidase activity of receptordestroying enzyme (RDE) compounds using the influenza virus.].  |  Fedorov, AY. and Zhirnov, OP. 2020. Vopr Virusol. 65: 113-118. PMID: 32515567
  9. The role of Neu1 in the protective effect of dipsacoside B on acetaminophen-induced liver injury.  |  Chen, S., et al. 2020. Ann Transl Med. 8: 823. PMID: 32793668
  10. Novel Molecular Mechanism of Aspirin and Celecoxib Targeting Mammalian Neuraminidase-1 Impedes Epidermal Growth Factor Receptor Signaling Axis and Induces Apoptosis in Pancreatic Cancer Cells.  |  Qorri, B., et al. 2020. Drug Des Devel Ther. 14: 4149-4167. PMID: 33116404
  11. Inhibiting Sialidase-Induced TGF-β1 Activation Attenuates Pulmonary Fibrosis in Mice.  |  Karhadkar, TR., et al. 2021. J Pharmacol Exp Ther. 376: 106-117. PMID: 33144389
  12. Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy.  |  Pila-Castellanos, I., et al. 2021. PLoS Pathog. 17: e1009340. PMID: 33596274
  13. Soybean phytochemicals responsible for bacterial neuraminidase inhibition and their characterization by UPLC-ESI-TOF/MS.  |  Baiseitova, A., et al. 2022. Food Funct. 13: 6923-6933. PMID: 35695875
  14. New dihydrobenzoxanthone derivatives with bacterial neuraminidase inhibitory activity isolated from Artocarpus elasticus.  |  Baiseitova, A., et al. 2022. Bioorg Chem. 127: 105978. PMID: 35752099

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt, 1 mg

sc-251885
1 mg
$69.00

2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt, 5 mg

sc-251885A
5 mg
$170.00

2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt, 25 mg

sc-251885B
25 mg
$769.00