Molecular structure of 2′/3′-O-Acetyl ADP Ribose, CAS Number: 1312013-29-8
2′/3′-O-Acetyl ADP Ribose (CAS 1312013-29-8)
Alternate Names:
2′/3′-O-Acetyl ADP Ribose is known as protein deacetylated NAD metabolites.
Application:
2′/3′-O-Acetyl ADP Ribose is a metabolite product of the sirtuin-mediated protein deacetylation of Nicotinamide adenine dinucleotide.
CAS Number:
1312013-29-8
Molecular Weight:
645.32
Molecular Formula:
C17H23N5Na2O15P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2′/3′-O-Acetyl ADP Ribose is produced as a metabolite from the sirtuin-mediated protein deacetylation of Nicotinamide adenine dinucleotide. Sirtuins, an ancient class of enzymes present in all organisms, first transfer acetate from Nε-acetyllysine residue to NAD. Water displaces nicotinamide and 2′/3′-O-Acetyl ADP Ribose is generated, rapidly equilibrating to a mixture of esters. Evidence suggests that 2′/3′-O-Acetyl ADP Ribose, as a mixture of the 2′- and 3′- isomers, functions as an intracellular second messenger. At neutral pH, the isomers of 2′/3′-O-Acetyl ADP Ribose exist in a ~1:1 ratio and are generated through a non-enzymatic fashion of intramolecular transesterification.
2′/3′-O-Acetyl ADP Ribose (CAS 1312013-29-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′/3′-O-Acetyl ADP Ribose, 2.5 mg | sc-481663 | 2.5 mg | $406.00 |