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2′,3′-Dideoxyguanosine is a nucleoside analog that is of particular interest in the field of molecular biology and genetics. It is incorporated into studies involving the inhibition of nucleic acid synthesis, as the absence of hydroxyl groups at the 2′ and 3′ positions of the sugar moiety prevents further extension of the nucleic acid chain. Researchers utilize 2′,3′-Dideoxyguanosine to understand the mechanisms of DNA replication and to investigate the termination of chain elongation in vitro. This compound is also used in enzymology to study the substrate specificity and kinetics of DNA polymerases and nucleotidyl transferase enzymes. In the area of structural biology, it serves as a tool for crystallography experiments to resolve the three-dimensional structures of nucleic acid-protein complexes. Additionally, 2′,3′-Dideoxyguanosine is relevant in the synthesis of oligonucleotides with specific modifications for use in molecular diagnostics and genetic research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′,3′-Dideoxyguanosine, 25 mg | sc-283506 | 25 mg | $102.00 | |||
2′,3′-Dideoxyguanosine, 50 mg | sc-283506A | 50 mg | $163.00 |