Date published: 2026-4-24

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2′,3′-Di-O-acetyladenosine (CAS 29886-19-9)

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Alternate Names:
Adenosine 2′,3′-diacetate
Application:
2′,3′-Di-O-acetyladenosine is an enzyme inhibitor
CAS Number:
29886-19-9
Purity:
≥98%
Molecular Weight:
351.31
Molecular Formula:
C14H17N5O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2′,3′-Di-O-acetyladenosine is a compound utilized in various research fields, including nucleic acid chemistry and enzymology. In studies of nucleic acids, it serves as a modified nucleoside that can be incorporated into oligonucleotides to investigate the effects of acetylation on the structure, stability, and function of RNA and DNA. Enzymologists may employ 2′,3′-Di-O-acetyladenosine to examine the specificity and mechanism of action of nucleoside deacetylases and other enzymes that recognize acetylated substrates. This compound is also a key intermediate in the chemical synthesis of more complex nucleoside derivatives, which are of interest for their potential in studying protein-nucleic acid interactions. Furthermore, it is used in the development of analytical methods for the detection and quantification of acetylated nucleosides. The research involving 2′,3′-Di-O-acetyladenosine enhances the understanding of acetylation′s role in modulating nucleic acid properties and enzyme-substrate interactions.


2′,3′-Di-O-acetyladenosine (CAS 29886-19-9) References

  1. Mimicking dominant negative inhibition of prion replication through structure-based drug design.  |  Perrier, V., et al. 2000. Proc Natl Acad Sci U S A. 97: 6073-8. PMID: 10823951
  2. Synthesis and evaluation of analogues of 5'-([(Z)-4-amino-2-butenyl]methylamino)-5'-deoxyadenosine as inhibitors of tumor cell growth, trypanosomal growth, and HIV-1 infectivity.  |  Marasco, CJ., et al. 2002. J Med Chem. 45: 5112-22. PMID: 12408722
  3. Peptidyl-donor substrates for ribosomal peptidyl transferase. Chemical synthesis and biological activity of N-acetyl aminoacyl di- and tri-nucleotides.  |  Mercer, JF. and Symons, RH. 1972. Eur J Biochem. 28: 38-45. PMID: 5050259
  4. Synthesis of [35S]thiophosphoryl adenylic acid, utilizing a general procedure for [35S]thiophosphoryl chloride production.  |  Slama, JT., et al. 1993. Anal Biochem. 209: 143-9. PMID: 8465947

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2′,3′-Di-O-acetyladenosine, 1 g

sc-214079
1 g
$71.00