raised against 26S Proteasome purified from embryos of Drosophila melanogaster origin
26S Proteasome p42C Antibody (9E3) is recommended for detection of p42C subunit of the 19S regulatory base complex of the 26S Proteasome of d origin by WB and IP
Anti-26S Proteasome p42C Antibody (9E3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of 26S Proteasome p42C (9E3): sc-65752.
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
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Labware ships FedEx Ground free of charge to the contiguous US
26S Proteasome p42C Antibody (9E3) is a high quality monoclonal 26S Proteasome p42C antibody (also designated 26S Proteasome p42C antibody) suitable for the detection of the 26S Proteasome p42C protein of Drosophila melanogaster origin. 26S Proteasome p42C Antibody (9E3) is available as both the non-conjugated anti-26S Proteasome p42C antibody form, as well as multiple conjugated forms of anti-26S Proteasome p42C antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The 26S proteasome is a large complex involved in the intracellular degradation of proteins in eukaryotes. Ubiquitination by E3 ubiquitin ligases targets proteins for degradation by this complex. The 26S proteasome plays an important role in the regulation of many biological processes. It is composed of over 30 different subunits and contains at least two copies of each subunit. Assembly of this large complex is ATP-dependent. Due to its size, it is fairly unstable and often disassociates into subcomplexes (including a 20S core and two 19S regulatory complexes). The 26S proteasome p42C (also known as Rpt6 in yeast and S8 in human) is one of the six ATPase base subunits of the 19S regulatory complex. The 19S regulatory complex recognizes ubiquitinated proteins, removes the ubiquitin chains and translocates the proteins to the 20S core for degradation. The 26S proteasome p42C may play a role in recruiting ubiquitination machineries.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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