Molecular structure of 25-Desacetyl Rifampicin, CAS Number: 16783-99-6
25-Desacetyl Rifampicin (CAS 16783-99-6)
Alternate Names:
25-O-Deacetyl-3-[(E)-[(4-methyl-1-piperazinyl)imino]methyl]rifamycin; 25-Deacetylrifampicin
Application:
25-Desacetyl Rifampicin is a metabolite of Rifampicin
CAS Number:
16783-99-6
Purity:
≥95%
Molecular Weight:
780.90
Molecular Formula:
C41H56N4O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
25-Desacetyl Rifampicin is a metabolite of Rifampicin. Utilizing 25-Desacetyl Rifampicin, researchers have conducted laboratory studies aiming to unravel the impacts of rifampicin on diverse biological processes. Its application spans the investigation of rifampicin′s mechanisms of action, elucidating its effects on both bacterial and mammalian cell cultures. Moreover, 25-Desacetyl Rifampicin has played a role in studying the influence of rifampicin on gene expression and protein synthesis.
25-Desacetyl Rifampicin (CAS 16783-99-6) References
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- The WHO simplified study protocol in practice: investigation of combined formulations supplied by the WHO. | Panchagnula, R., et al. 1999. Int J Tuberc Lung Dis. 3: S336-42; discussion S351-2. PMID: 10593714
- Evaluation of the recently reported USP gradient HPLC method for analysis of anti-tuberculosis drugs for its ability to resolve degradation products of rifampicin. | Mohan, B., et al. 2003. J Pharm Biomed Anal. 31: 607-12. PMID: 12615251
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- A bioequivalence comparison of two formulations of rifampicin (300- vs 150-mg capsules): An open-label, randomized, two-treatment, two-way crossover study in healthy volunteers. | Chik, Z., et al. 2010. Clin Ther. 32: 1822-31. PMID: 21194606
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- Troubleshooting carry-over of LC-MS/MS method for rifampicin, clarithromycin and metabolites in human plasma. | Vu, DH., et al. 2013. J Chromatogr B Analyt Technol Biomed Life Sci. 917-918: 1-4. PMID: 23353809
- Relationship between CES2 genetic variations and rifampicin metabolism. | Song, SH., et al. 2013. J Antimicrob Chemother. 68: 1281-4. PMID: 23471941
- Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing. | Sengupta, S., et al. 2014. Toxicol Sci. 140: 236-45. PMID: 24752503
- Population Pharmacokinetic Analysis of Rifampicin in Plasma, Cerebrospinal Fluid, and Brain Extracellular Fluid in South African Children with Tuberculous Meningitis. | Abdelgawad, N., et al. 2023. Antimicrob Agents Chemother. 67: e0147422. PMID: 36815838
- In vitro effect of rifampicin and its derivatives on energy transfer reactions in mitochondria. | Inouye, B., et al. 1974. J Antibiot (Tokyo). 27: 192-8. PMID: 4275810
- Determination of rifampicin and its main metabolite in plasma and urine in presence of pyrazinamide and isoniazid by HPLC method. | Panchagnula, R., et al. 1999. J Pharm Biomed Anal. 18: 1013-20. PMID: 9925337
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
25-Desacetyl Rifampicin, 1 mg | sc-206558 | 1 mg | $265.00 |