24(S),25-Epoxycholesterol (CAS 77058-74-3)
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24(S),25-Epoxycholesterol is a sterol derivative that plays a role in the regulation of cholesterol homeostasis. It is involved in the modulation of cellular cholesterol levels through the activation of liver X receptors (LXRs), which are nuclear receptors that control the expression of genes involved in cholesterol metabolism. It is synthesized in response to high levels of cellular cholesterol and functions as a signaling molecule to activate LXRs, leading to the upregulation of genes involved in cholesterol efflux and excretion. 24(S),25-Epoxycholesterol inhibits the processing of sterol regulatory element-binding proteins (SREBPs), which are transcription factors that regulate the expression of genes involved in cholesterol and fatty acid synthesis. Through these mechanisms, 24(S),25-Epoxycholesterol contributes to the maintenance of cholesterol homeostasis and the prevention of cholesterol accumulation in cells.
24(S),25-Epoxycholesterol (CAS 77058-74-3) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
24(S),25-Epoxycholesterol, 1 mg | sc-471354 | 1 mg | $326.00 |