Molecular structure of 22-Oxacalcitriol, CAS Number: 103909-75-7
22-Oxacalcitriol (CAS 103909-75-7)
See product citations (3)
Alternate Names:
Maxacalcitrol
Application:
22-Oxacalcitriol is a Vitamin D3 analog and VDR ligand
CAS Number:
103909-75-7
Purity:
≥95%
Molecular Weight:
418.61
Molecular Formula:
C26H42O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Product Citations
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
22-Oxacalcitriol a Vitamin D3 analog and VDR ligand. Has been shown to decrease parathyroid hormone (PTH) mRNA expression in vitro.
22-Oxacalcitriol (CAS 103909-75-7) References
- 22-oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. | Monier-Faugere, MC., et al. 1999. Kidney Int. 55: 821-32. PMID: 10027919
- Inhibitory effects of 22-oxa-calcitriol and all- trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. | Barroga, EF., et al. 2000. Res Vet Sci. 68: 79-87. PMID: 10684763
- The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion. | Nishii, Y., et al. 1991. Contrib Nephrol. 91: 123-8. PMID: 1800003
- 22-Oxacalcitriol prevents progression of peritoneal fibrosis in a mouse model. | Hirose, M., et al. 2013. Perit Dial Int. 33: 132-42. PMID: 23032084
- Clinical uses of 22-oxacalcitriol. | Mizobuchi, M. and Ogata, H. 2014. Curr Vasc Pharmacol. 12: 324-8. PMID: 23713875
- 22-Oxacalcitriol attenuates bone loss in nonobese type 2 diabetes. | Goto, S., et al. 2015. Bone. 74: 153-9. PMID: 25645030
- 22-oxacalcitriol prevents acute kidney injury via inhibition of apoptosis and enhancement of autophagy. | Hamzawy, M., et al. 2019. Clin Exp Nephrol. 23: 43-55. PMID: 29968126
- 22-oxacalcitriol protects myocardial ischemia-reperfusion injury by suppressing NF-κB/TNF-α pathway. | Zhou, CN., et al. 2019. Eur Rev Med Pharmacol Sci. 23: 5495-5502. PMID: 31298403
- Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo. | Merrigan, SL., et al. 2020. Oncotarget. 11: 493-509. PMID: 32082484
- 22-Oxacalcitriol does not interfere with parathyroid hormone-induced phosphaturia or cyclic-AMP excretion. | Friedlaender, MM., et al. 1995. Bone. 17: 301-6. PMID: 8541145
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
22-Oxacalcitriol, 1 mg | sc-361076 | 1 mg | $175.00 |