20S Proteasome α1/α2/α3/α5/α6/α7 Antibody (MCP231): sc-58412

20S Proteasome α1/α2/α3/α5/α6/α7 Antibody (MCP231) is a mouse monoclonal IgG1 antibody that detects 20S Proteasome in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. 20S Proteasome is a crucial component of the proteasome complex, which plays a vital role in maintaining cellular homeostasis by degrading unnecessary or damaged proteins through proteolysis. This process is essential for regulating various cellular functions, including the cell cycle, signal transduction, and the response to oxidative stress. The 20S Proteasome core particle, which is hollow and contains a series of subunits, allows for the selective entry of target proteins, ensuring that only those marked for degradation are processed. The structural integrity of 20S Proteasome is paramount, as 20S Proteasome consists of a combination of α and β subunits that form a cylindrical structure, with the α subunits serving as gates that control access to the catalytic β subunits within. This precise architecture not only facilitates efficient protein degradation but also prevents the uncontrolled breakdown of cellular proteins, thereby safeguarding cellular function and integrity. Anti-20S Proteasome antibody (MCP231) is an invaluable tool for researchers studying proteasome activity and its implications in various biological processes and diseases.

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The preferred 20S Proteasome α3 antibody is 20S Proteasome α3 Antibody (A-9): sc-166205.