Date published: 2026-3-18

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(20S)-21-Hydroxy-20-methylpregn-4-en-3-one (CAS 40736-33-2)

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Alternate Names:
23,24-Bisnorchol-4-en-3-on-22-ol; 3-keto-23,24-Bisnorchol-4-en-22-ol
CAS Number:
40736-33-2
Molecular Weight:
330.5
Molecular Formula:
C22H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(20S)-21-Hydroxy-20-methylpregn-4-en-3-one is a compound that serves as a side chain degradation product of natural sterols. It is also used as an intermediate in the synthesis of follicular fluid-meiosis activating sterol. In biochemical research and industrial applications, such steroids are of interest for their role in understanding steroid metabolism and biosynthesis. They can serve as precursors or intermediates in the synthesis of more complex steroids, contributing to the study of steroidogenesis pathways and the exploration of their mechanisms of action within organisms.


(20S)-21-Hydroxy-20-methylpregn-4-en-3-one (CAS 40736-33-2) References

  1. Downstream Process Synthesis for Microbial Steroids.  |  Thygs, FB. and Merz, J. 2017. Methods Mol Biol. 1645: 321-345. PMID: 28710639
  2. Identification of key sites determining the cofactor specificity and improvement of catalytic activity of a steroid 5β-reductase from Capsella rubella.  |  Li, Y., et al. 2020. Enzyme Microb Technol. 134: 109483. PMID: 32044030
  3. Synthesis of ursodeoxycholic acid from plant-source (20S)-21-hydroxy-20-methylpregn-4-en-3-one.  |  Wang, J., et al. 2020. Steroids. 157: 108600. PMID: 32068080
  4. Synthesis of ursodeoxycholic acid by electrochemical stereoselective reduction of 7-ketolithocholic acid in aprotic solvents.  |  Shen, J., et al. 2021. Sci Rep. 11: 16273. PMID: 34381112
  5. Synthesis of plant-derived cholesterol from bisnoralcohol.  |  Li, XZ., et al. 2022. Steroids. 178: 108967. PMID: 35085676

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(20S)-21-Hydroxy-20-methylpregn-4-en-3-one, 10 mg

sc-489938
10 mg
$300.00