Molecular structure of 20-COOH-LTB4, CAS Number: 80434-82-8
20-COOH-LTB4 (CAS 80434-82-8)
Application:
20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways
CAS Number:
80434-82-8
Purity:
>97%
Molecular Weight:
366.5
Molecular Formula:
C20H30O6
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
20-COOH-LTB4 is an omega-oxidized metabolite of leukotriene B4 (sc-201043). Leukotrienes have been shown to be potent eicosanoid lipid mediators derived from phospholipase-released Arachidonic Acid (sc-200770). These compounds have been reported to be involved in inflammation and numerous homeostatic biological functions. In rat hepatocytes, 20-COOH-LTB4 is noted to be a substrate for beta-oxidation pathways found in peroxisomes and mitochondria.
20-COOH-LTB4 (CAS 80434-82-8) References
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- NAD+-dependent conversion of 20-OH-LTB4 to 20-COOH-LTB4 by a cell-free system of human polymorphonuclear leukocytes. | Sumimoto, H., et al. 1985. Biochem Biophys Res Commun. 132: 864-70. PMID: 3000366
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- Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes. | Shak, S. and Goldstein, IM. 1984. J Biol Chem. 259: 10181-7. PMID: 6088485
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
20-COOH-LTB4, 50 µg | sc-201540 | 50 µg | $650.00 | |||
20-COOH-LTB4, 250 µg | sc-201540A | 250 µg | $2000.00 |