Date published: 2025-10-19

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2-(Trifluoromethyl)styrene (CAS 395-45-9)

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CAS Number:
395-45-9
Molecular Weight:
172.15
Molecular Formula:
C9H7F3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(Trifluoromethyl)styrene is an extremely versatile and reactive organic compound that finds widespread applications in both scientific research and industrial production. It exists as a colorless and volatile liquid. 2-(Trifluoromethyl)styrene represents a structural isomer of styrene and is alternatively known as 3,4-difluorostyrene. Its chemical structure comprises a phenyl ring combined with two trifluoromethyl substituents, featuring a double bond connecting the two carbon atoms within the ring. Due to its electron-rich structure, 2-(Trifluoromethyl)styrene is characterized by its high reactivity, enabling it to undergo diverse chemical reactions, including addition, substitution, and elimination reactions. It can also engage in polymerization and cross-linking reactions. This exceptional reactivity stems from its electron-rich configuration, rendering it an ideal substrate for numerous reaction types.


2-(Trifluoromethyl)styrene (CAS 395-45-9) References

  1. Continuous flow system with a polymer-supported dirhodium(II) catalyst: application to enantioselective carbonyl ylide cycloaddition reactions.  |  Takeda, K., et al. 2011. Chemistry. 17: 13992-8. PMID: 22095784
  2. Enantioselective manganese-porphyrin-catalyzed epoxidation and C-H hydroxylation with hydrogen peroxide in water/methanol solutions.  |  Srour, H., et al. 2012. Inorg Chem. 51: 5850-6. PMID: 22568436
  3. Substituent Effects in the Surface-Initiated ATRP of Substituted Styrenes.  |  Saha, S. and Baker, GL. 2015. Appl Surf Sci. 359: 911-916. PMID: 26692601
  4. Divergent Functionalization of Styrenes via Radical/Polar Crossover with CO2 and Sodium Sulfinates.  |  Benedetti Vega, K., et al. 2023. Chemistry. 29: e202203625. PMID: 36571402

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(Trifluoromethyl)styrene, 1 g

sc-259402
1 g
$62.00