2-trans,7-cis,10-cis,13-cis,16-cis-Docosapentaenoic acid (CAS 205519-75-1)

2-trans,7-cis,10-cis,13-cis,16-cis-Docosapentaenoic acid, identified by CAS number 205519-75-1, is a complex polyunsaturated fatty acid featuring a unique pattern of double bonds, including a trans configuration at the second position and cis configurations at the 7th, 10th, 13th, and 16th positions along its 22-carbon chain. This complex structure categorizes it as a variant within the extensive family of docosapentaenoic acids, which are typically studied for their role in modulating biophysical properties of cell membranes. The unusual combination of trans and cis double bonds significantly influences the three-dimensional shape of the molecule, which in turn affects its interaction with other lipid molecules within the membrane bilayer. In research, this fatty acid has been particularly valuable in exploring the effects of fatty acid geometry on membrane fluidity, phase behavior, and the organization of lipid domains, which are critical for maintaining cellular functionality and integrity. The trans bond introduces a kink that alters packing properties and has implications for the membrane′s physical state and its biological activities. Studies involving 2-trans,7-cis,10-cis,13-cis,16-cis-Docosapentaenoic acid contribute to a deeper understanding of lipid-mediated processes at the molecular level, such as signal transduction and the regulation of membrane-bound enzymes and receptors. This research aids in deciphering the fundamental mechanisms by which lipid diversity influences cellular behavior and response mechanisms in various environmental and physiological contexts.