2-trans,10-cis,13-cis,16-cis-Docosatetraenoic acid (CAS 1211930-10-7)

2-trans,10-cis,13-cis,16-cis-Docosatetraenoic acid, cataloged under CAS number 1211930-10-7, is a specialized form of polyunsaturated fatty acid distinguished by its unique configuration of one trans and three cis double bonds positioned at the 2nd, 10th, 13th, and 16th carbons in its 22-carbon chain. This structural arrangement imparts distinctive biophysical properties to the fatty acid, particularly influencing the way it integrates into and affects cell membrane dynamics. In research, this acid is utilized to study the impact of mixed double bond orientations on the lipid bilayer′s fluidity, phase behavior, and overall structural organization. The presence of a trans bond amidst cis configurations introduces specific kinks and bends in the molecular shape, which can disrupt the regular packing of lipids within membranes, thereby altering membrane properties such as permeability, flexibility, and the activity of membrane-bound proteins. These studies are crucial for understanding how variations in lipid composition can modulate cell signaling and interaction, potentially influencing broader cellular functions. By examining the effects of such unique fatty acids, researchers gain insights into the molecular mechanisms governing cell membrane behavior, contributing valuable knowledge to the fields of biochemistry and cell physiology, particularly in understanding how cells adapt to and manage various environmental stresses and stimuli.