Date published: 2026-3-14

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2-Thiophenecarbonyl chloride (CAS 5271-67-0)

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Alternate Names:
Thiophene-2-carbonyl chloride; 2-Thenoyl Chloride
Application:
2-Thiophenecarbonyl chloride is used in the synthesis of building blocks
CAS Number:
5271-67-0
Purity:
≥97%
Molecular Weight:
146.59
Molecular Formula:
C5H3ClOS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Thiophenecarbonyl chloride is a chemical compound that functions as an acylating agent in organic synthesis reactions. It is involved in the formation of amides, esters, and other functional groups through acylation processes. The mode of action of 2-Thiophenecarbonyl chloride involves the transfer of its acyl group to nucleophilic sites on other molecules, leading to the formation of new chemical bonds. This compound is known to react with a variety of nucleophiles, including amines, alcohols, and thiols, resulting in the introduction of the acyl group into the target molecules. In this way, 2-Thiophenecarbonyl chloride plays a role in the modification and functionalization of organic compounds, contributing to the synthesis of diverse chemical products.


2-Thiophenecarbonyl chloride (CAS 5271-67-0) References

  1. Synthesis, structure, and electrocatalysis of diiron C-functionalized propanedithiolate (PDT) complexes related to the active site of [FeFe]-hydrogenases.  |  Song, LC., et al. 2008. Inorg Chem. 47: 4545-53. PMID: 18439002
  2. New basic insight into reductive functionalization sequences of single walled carbon nanotubes (SWCNTs).  |  Hof, F., et al. 2013. J Am Chem Soc. 135: 18385-95. PMID: 24256165
  3. A selective N,N-dithenoyl-rhodamine based fluorescent probe for Fe3+ detection in aqueous and living cells.  |  Liu, Y., et al. 2020. J Environ Sci (China). 90: 180-188. PMID: 32081314

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Thiophenecarbonyl chloride, 25 g

sc-238216
25 g
$19.00