Date published: 2025-11-11

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2-thioacetyl MAGE (CAS 112014-15-0)

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Application:
2-thioacetyl MAGE is a colorimetric substrate for AADACL1 (KIAA1363)
CAS Number:
112014-15-0
Molecular Weight:
374.62
Molecular Formula:
C21H42O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-thioacetyl MAGE, cataloged under CAS number 112014-15-0, is a synthetic compound that belongs to a broader group of chemicals known as glycopeptides. This particular molecule is intriguing due to its modified peptide structure, which includes a thioacetyl group attached to a melanoma-associated glycopeptide (MAGE). The presence of the thioacetyl group introduces unique chemical properties, notably in the realm of sulfur-based reactivity, which can significantly influence the molecule′s stability and reactivity. In research contexts, 2-thioacetyl MAGE has been utilized primarily in studies focusing on peptide structure and function, particularly how modifications can affect peptide interactions with proteins and other biological macromolecules. The thioacetyl modification often serves as a probe in biochemical assays to understand peptide binding dynamics and to investigate the role of peptides in signaling pathways. This research can provide valuable insights into the design and synthesis of modified peptides for specific scientific applications, such as the creation of novel biomaterials or the development of peptide-based probes for various biochemical and biophysical studies. The unique structural features of 2-thioacetyl MAGE make it an important compound for examining the effects of thioacetyl modifications on peptide behavior and functionality within complex biological systems.


2-thioacetyl MAGE (CAS 112014-15-0) References

  1. An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling.  |  Chiang, KP., et al. 2006. Chem Biol. 13: 1041-50. PMID: 17052608
  2. Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1).  |  Shreder, KR., et al. 2012. Bioorg Med Chem Lett. 22: 5748-51. PMID: 22877630

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-thioacetyl MAGE, 1 mg

sc-205094
1 mg
$40.00

2-thioacetyl MAGE, 5 mg

sc-205094A
5 mg
$180.00