Date published: 2026-6-1

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2-Propyl-2-oxazoline (CAS 4694-80-8)

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CAS Number:
4694-80-8
Molecular Weight:
113.16
Molecular Formula:
C6H11NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Propyl-2-oxazoline, also known as 4,5-Dihydro-2-propyloxazole (DHP), has been instrumental in the synthesis of various organic compounds, including substances used in the creation of bioactive compounds, hormones, and vitamins. It has also found use in the creation of polymers, catalysts, and surfactants. Moreover, 2-Propyl-2-oxazoline has been utilized in the creation of a variety of compounds used in imaging and delivery processes. While the exact mechanism of action of 2-Propyl-2-oxazoline isn′t entirely clear, it′s believed to play a part in the creation of various organic compounds. It′s hypothesized to function as a nucleophile, reacting with a range of electrophiles, such as carbonyl compounds, carboxylic acids, and halides. This reaction is thought to involve the creation of a covalent bond between the nucleophile and the electrophile, leading to the formation of a new organic compound.


2-Propyl-2-oxazoline (CAS 4694-80-8) References

  1. Thermo-responsive polyoxazolines with widely tuneable LCST.  |  Diehl, C. and Schlaad, H. 2009. Macromol Biosci. 9: 157-61. PMID: 19009514
  2. Polyoxazoline: chemistry, properties, and applications in drug delivery.  |  Viegas, TX., et al. 2011. Bioconjug Chem. 22: 976-86. PMID: 21452890
  3. Structure-property relationship in cytotoxicity and cell uptake of poly(2-oxazoline) amphiphiles.  |  Luxenhofer, R., et al. 2011. J Control Release. 153: 73-82. PMID: 21513750
  4. Brachytherapy with Intratumoral Injections of Radiometal-Labeled Polymers That Thermoresponsively Self-Aggregate in Tumor Tissues.  |  Sano, K., et al. 2017. J Nucl Med. 58: 1380-1385. PMID: 28408533
  5. Unravelling the Excellent Chemical Stability and Bioavailability of Solvent Responsive Curcumin-Loaded 2-Ethyl-2-oxazoline-grad-2-(4-dodecyloxyphenyl)-2-oxazoline Copolymer Nanoparticles for Drug Delivery.  |  Datta, S., et al. 2018. Biomacromolecules. 19: 2459-2471. PMID: 29634248
  6. Stimuli-responsive self-assembly of cellulose nanocrystals (CNCs): Structures, functions, and biomedical applications.  |  Ganguly, K., et al. 2020. Int J Biol Macromol. 155: 456-469. PMID: 32222290
  7. Synthesis and Structure-Property Relationship of Amphiphilic Poly(2-ethyl-co-2-(alkyl/aryl)-2-oxazoline) Copolymers.  |  Kohlan, TB., et al. 2022. ACS Omega. 7: 40067-40077. PMID: 36385860

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Propyl-2-oxazoline, 1 g

sc-473773
1 g
$188.00