2-Propanol-1,1,1,3,3,3-d6 (CAS 3976-29-2)

2-Propanol-1,1,1,3,3,3-d6, commonly referred to as deuterated isopropanol, is a chemical variant of isopropanol in which most of the hydrogen atoms are replaced with deuterium, a heavier isotope of hydrogen. This isotopic substitution significantly alters the physical and chemical properties of the alcohol, particularly in the context of Nuclear Magnetic Resonance (NMR) spectroscopy, where it is extensively used. In NMR spectroscopy, the use of deuterated isopropanol helps in obtaining clearer, less cluttered spectra. Hydrogen, which normally produces complex splitting patterns and intense signals in NMR, is replaced by deuterium, which has a much weaker interaction with the magnetic field, thus simplifying the spectra and making it easier to interpret the structural details of the molecule being studied. Additionally, the introduction of deuterium alters the vibrational modes of the molecule, which is exploited in infrared spectroscopy and other vibrational spectroscopy techniques to study molecular interactions and dynamics. The kinetic isotope effect, where reactions involving deuterated compounds proceed at different rates compared to their non-deuterated counterparts, also makes 2-Propanol-1,1,1,3,3,3-d6 a valuable tool in chemical kinetics and mechanism studies, providing insights into the intricacies of reaction pathways and molecular behavior in various chemical environments.