2′,3′-cGAMP (CAS 1441190-66-4)
Alternate Names:
2′-3′-cyclic GMP-AMP
CAS Number:
1441190-66-4
Molecular Weight:
674.40
Molecular Formula:
C20H24N10O13P2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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2′,3′-cGAMP (CAS 1441190-66-4) References
- Ancient Origin of cGAS-STING Reveals Mechanism of Universal 2',3' cGAMP Signaling. | Kranzusch, PJ., et al. 2015. Mol Cell. 59: 891-903. PMID: 26300263
- DNA-induced 2'3'-cGAMP enhances haplotype-specific human STING cleavage by dengue protease. | Su, CI., et al. 2020. Proc Natl Acad Sci U S A. 117: 15947-15954. PMID: 32576686
- The cyclic dinucleotide 2'3'-cGAMP induces a broad antibacterial and antiviral response in the sea anemone Nematostella vectensis. | Margolis, SR., et al. 2021. Proc Natl Acad Sci U S A. 118: PMID: 34903650
- Protocol for identification and validation of 2'3'-cGAMP-binding proteins by photoaffinity probes. | Hou, Y., et al. 2022. STAR Protoc. 3: 101076. PMID: 35036957
- Arabinose- and xylose-modified analogs of 2',3'-cGAMP act as STING agonists. | Xie, W., et al. 2023. Cell Chem Biol. 30: 1366-1376.e7. PMID: 37536341
- Investigating the Evolution of Drosophila STING-Dependent Antiviral Innate Immunity by Multispecies Comparison of 2'3'-cGAMP Responses. | Hédelin, L., et al. 2024. Mol Biol Evol. 41: PMID: 38377349
- STING activator 2'3'-cGAMP enhanced HSV-1-based oncolytic viral therapy. | Sibal, PA., et al. 2024. Mol Oncol. 18: 1259-1277. PMID: 38400597
- The efficient synthesis and purification of 2'3'- cGAMP from Escherichia coli. | Kulkarni, R., et al. 2024. Front Microbiol. 15: 1345617. PMID: 38525075
- Combination of STING agonist with anti-vascular RGD-(KLAKLAK)2 peptide as a novel anti-tumor therapy. | Czapla, J., et al. 2024. Cancer Immunol Immunother. 73: 148. PMID: 38832958
- Unraveling the Binding Mode of Cyclic Adenosine-Inosine Monophosphate (cAIMP) to STING through Molecular Dynamics Simulations. | Wang, M., et al. 2024. Molecules. 29: PMID: 38893524
Activator of:
AIM2, CMPK2, DDX60L, IFI-16, IFI-35, IFN-α1, IFN-ω, IL-26, ISG15, MAVS, Mx2, NOD3, Optineurin, RP105, TBK1, TMED1, TMEM173, and ZBP1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′,3′-cGAMP, 10 mg | sc-507484 | 10 mg | $1800.00 |