Molecular structure of 2-(Phosphonomethyl)-pentanedioic acid, CAS Number: 173039-10-6
2-(Phosphonomethyl)-pentanedioic acid (CAS 173039-10-6)
Alternate Names:
PMPA
Application:
2-(Phosphonomethyl)-pentanedioic acid is an inhibitor of the neuropeptidase NAALADase
CAS Number:
173039-10-6
Purity:
≥97%
Molecular Weight:
226.1
Molecular Formula:
C6H11O7P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-(Phosphonomethyl)-pentanedioic acid is a potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase (NAALADase), which is a membrane-bound peptidase that hydrolyses N-acetyl-L-aspartate-L-glutamate (NAAG), a major brain peptide.
2-(Phosphonomethyl)-pentanedioic acid (CAS 173039-10-6) References
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase: P.F. Jackson, et al.; J. Med. Chem. 39, 619 (1996) Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II: R. Luthi-Carter, et al.; Brain Res. 795, 341 (1998)Inhibitor of:
Enzyme, and PSM.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-(Phosphonomethyl)-pentanedioic acid, 1 mg | sc-220669 | 1 mg | $58.00 | |||
2-(Phosphonomethyl)-pentanedioic acid, 5 mg | sc-220669A | 5 mg | $235.00 |